Gene: TCF7L2 ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs386418874
rs386418874
TCF7L2
0.700 GeneticVariation GWASCAT ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. 31324766

2019
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. 31118516

2019
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Fine-mapping of the TCF7L2 locus suggested one type 2 diabetes association signal shared between Europeans and Africans (indexed by rs7903146) and a distinct African-specific signal (indexed by rs17746147). 31049640

2019
dbSNP: rs7901695
rs7901695
TCF7L2
C 0.900 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019
dbSNP: rs7903146
rs7903146
TCF7L2
0.900 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs117229942
rs117229942
TCF7L2
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs4918796
rs4918796
TCF7L2
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs7903146
rs7903146
TCF7L2
C 0.900 GeneticVariation GWASCAT Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia. 30470734

2018
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia. 30470734

2018
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs117229942
rs117229942
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs4918796
rs4918796
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. 29358691

2018
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). 28254843

2017
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. 27189021

2016
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility. 25483131

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 25102180

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASDB Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014